Avian Homology on High Diversity Sequences Distinguished Across Globe
On 2011-12-20, the UK National Institute of Medical Research released a group of human pH1N1 sequences at GISAID including 46 full HA and 45 full NA segments. The sample dates cover 2010-12-15 to 2011-08-11 (44 during 2011). Fifteen originating labs provided the samples though no specification of clinical outcome is notated within the NIMR deposit.
The volume and span of the deposit demonstrates the ongoing significant rate of genetic acquisition onto 4 of the established clades, alongside several uncladed sequences. Four sequences carry clade-defining elements from multiple clades. Ambiguity in the traces is high with 44 mixed traces. This deposit brings the first pH1N1 sequence with a combined 40 polymorphisms (HA and NA) on the highly avian-influenced, SenegalDakar14_1x_2011_04_14 (HA 29 / NA 11) [EPI346724]. A certain population of geographically-dispersed sequences shows a combined HA and NA total of 25 or more revisions (10 sequences, 22% of the deposit).
Enhanced acquisition of avian genetic data and convergence of polymorphisms found on high-CFR and high-zoonotic pH1N1 strains are quantified. Variant clades appear to be gaining data from the same sources as the pH1N1 HA 230I strains and the Upsilon series of 84 sequences (5.33% CFR).
Five countries (Cameroon, France, England, Iceland and Hungary) produced a subset of 9 sequences bearing 12 polymorphisms within the aa156-aa159 range, a domain documented to produce Vaccine Escape. Hungary7_xM_2011_01_31 (HA 11 / NA 06) [EPI346709] on Clade2: 188T with RBS 226R (Vaccine Match) applies polymorphic behaviour at 3 consecutive Vaccine Escape locations in this domain (HA 157E mix wt, 158E mix wt and 159D mix wt).
One sequence is TamiFlu Resistant with NA 275Y. More importantly a strong gravity is indicated in the polymorphic pattern suggestive that more TmX due to NA 247N will be seen in the future on these types of strains. Considering the HA and NA distinct polymorphic supersets on these human pandemic sequences, 36 changes (10%) appear on earlier pandemic sequences with TmX due to NA 247N and 81 changes (23%) appear on the subset of H5N1 sequences that carry the NA 247N marker.
Evaluating the 226 distinct HA changes derived from these 46 human pandemic sequences against fractional HA subsets of several animal serotypes, a minimum of 72% share homology. Avian H1N1 leads the match count at 115 polymorphic positions while H6N1 continues to participate at a significant level (79 matches). Homology to Avian H9N2 (62), H13 (52) and the High-CFR H5N1 (50) demonstrates that this pandemic has ample opportunity for genetic input from the extant reservoirs to amplify clinical conditions.
Though the zoonotic serotype backgrounds profiled against these human polymorphisms are entirely variant, these many codon-level homologies crossing multiple zoonotic reservoirs into the human pandemic illuminates the GeneWurx premise that the origin of the human H1N1 pandemic be reconsidered as avian.
One TamiFlu Resistant sequence (NA 275Y) features on a Clade2: 188T background and carries HA RBS 227G with the HA 158E (mixture with wild type) that has repeatedly been observed to promote Vaccine Escape.
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1973-1982: Israel and Jordan Support Muslim Brotherhood Terrorism Against Syria
Early 1981: Mossad Initiates Bombing Campaign in Europe against A. Q. Khan Network
February 1982: Article in Israeli Journal Says Israel Should Exploit Internal Tensions of Arab States
1984-1989: Israeli Intelligence Officer Supplies Arms to Iran; Some Profits Allegedly Used to Fund False Flag Attacks
1987: Hamas Forms with the Support of Israeli Intelligence
February 6, 2000: Apparent Mossad Attempt to Infiltrate Al-Qaeda Thwarted
September 10, 2001: Army School Peacekeeping Report Says Mossad Can Target US Forces with False Flag Attacks
October 10, 2001: Two Israelis Are Detained in Mexican Legislature Building after Behaving Suspiciously and Found To Be Carrying Arms
February 5, 2003: Recently Retired Head of Mossad Says His Agency Has Had Many Secret Big Successes
March 2005: Israel Honors People Involved in Lavon Affair
Early June 2005: US Intelligence Find Evidence of Mossad or CIA Support For Insurgents in Iraq
November 9, 2005: Three Simultaneous Suicide Bombings in Jordan; Israeli Tourists Evacuated in Advance
http://www.historycommons.org/timeline.jsp?western_support_for_islamic_militancy_tmln_alleged_false_flag_operations=western_support_for_islamic_militancy_tmln_israel_and_the_mossad&timeline=western_support_for_islamic_militancy_tmln
On 2011-12-20, the UK National Institute of Medical Research released a group of human pH1N1 sequences at GISAID including 46 full HA and 45 full NA segments. The sample dates cover 2010-12-15 to 2011-08-11 (44 during 2011). Fifteen originating labs provided the samples though no specification of clinical outcome is notated within the NIMR deposit.
The volume and span of the deposit demonstrates the ongoing significant rate of genetic acquisition onto 4 of the established clades, alongside several uncladed sequences. Four sequences carry clade-defining elements from multiple clades. Ambiguity in the traces is high with 44 mixed traces. This deposit brings the first pH1N1 sequence with a combined 40 polymorphisms (HA and NA) on the highly avian-influenced, SenegalDakar14_1x_2011_04_14 (HA 29 / NA 11) [EPI346724]. A certain population of geographically-dispersed sequences shows a combined HA and NA total of 25 or more revisions (10 sequences, 22% of the deposit).
Enhanced acquisition of avian genetic data and convergence of polymorphisms found on high-CFR and high-zoonotic pH1N1 strains are quantified. Variant clades appear to be gaining data from the same sources as the pH1N1 HA 230I strains and the Upsilon series of 84 sequences (5.33% CFR).
Five countries (Cameroon, France, England, Iceland and Hungary) produced a subset of 9 sequences bearing 12 polymorphisms within the aa156-aa159 range, a domain documented to produce Vaccine Escape. Hungary7_xM_2011_01_31 (HA 11 / NA 06) [EPI346709] on Clade2: 188T with RBS 226R (Vaccine Match) applies polymorphic behaviour at 3 consecutive Vaccine Escape locations in this domain (HA 157E mix wt, 158E mix wt and 159D mix wt).
One sequence is TamiFlu Resistant with NA 275Y. More importantly a strong gravity is indicated in the polymorphic pattern suggestive that more TmX due to NA 247N will be seen in the future on these types of strains. Considering the HA and NA distinct polymorphic supersets on these human pandemic sequences, 36 changes (10%) appear on earlier pandemic sequences with TmX due to NA 247N and 81 changes (23%) appear on the subset of H5N1 sequences that carry the NA 247N marker.
Evaluating the 226 distinct HA changes derived from these 46 human pandemic sequences against fractional HA subsets of several animal serotypes, a minimum of 72% share homology. Avian H1N1 leads the match count at 115 polymorphic positions while H6N1 continues to participate at a significant level (79 matches). Homology to Avian H9N2 (62), H13 (52) and the High-CFR H5N1 (50) demonstrates that this pandemic has ample opportunity for genetic input from the extant reservoirs to amplify clinical conditions.
Though the zoonotic serotype backgrounds profiled against these human polymorphisms are entirely variant, these many codon-level homologies crossing multiple zoonotic reservoirs into the human pandemic illuminates the GeneWurx premise that the origin of the human H1N1 pandemic be reconsidered as avian.
One TamiFlu Resistant sequence (NA 275Y) features on a Clade2: 188T background and carries HA RBS 227G with the HA 158E (mixture with wild type) that has repeatedly been observed to promote Vaccine Escape.
H5N1 controversy: Too late to contain the research?
Getting Worse: 40 Undeniable pieces of evidence that show America is in decline
The Tools of America's Future Police State
14,000 US Dead in 14 Weeks After Fukushima Meltdown
US military: Unconstitutional orders are unlawful, defend Americans, don't NDAA "disappear" them
H5N1: The view from Hong Kong
Scientists defend 'Armageddon virus' secrecy
Too late to contain killer flu science, say experts
Weird CHEMBOW Over FUKUSHIMA DAIICHI 2011! HAARP or Chemtrail Phenomenon?
Santa Cruz Board Questions PG&E – SmartMeter ShutOffs
Judge says no to inquest on weapons inspector Dr Kelly/ Mail
12/20/2011 — Pacific Ring of fire, Puerto Rico, and South Africa = Volcanoes, Fracking, Plate unrest
Military to Designate U.S. Citizens as Enemy During Collapse
Chemtrails: More Desecration Of Halifax Skies
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April 1950: Anti-Jewish Bombings in Iraq Are Attributed to Israelis
July 1954: Israel Commits Bombing Attacks in Egypt, Tries to Blame Muslim Brotherhood
1967-2001: Israel Provides Support to Militant Islamic Groups in the West Bank and Gaza
September 6-12, 1970 and After: 'Black September' Triggers Global Islamist Terrorism, Rise of PLO
1973-1978: With Israel's support, Ahmed Yassin Forms Islamist Organizations in the West Bank and Gaza
1973-1982: Israel and Jordan Support Muslim Brotherhood Terrorism Against Syria
Early 1981: Mossad Initiates Bombing Campaign in Europe against A. Q. Khan Network
February 1982: Article in Israeli Journal Says Israel Should Exploit Internal Tensions of Arab States
1984-1989: Israeli Intelligence Officer Supplies Arms to Iran; Some Profits Allegedly Used to Fund False Flag Attacks
1987: Hamas Forms with the Support of Israeli Intelligence
February 6, 2000: Apparent Mossad Attempt to Infiltrate Al-Qaeda Thwarted
September 10, 2001: Army School Peacekeeping Report Says Mossad Can Target US Forces with False Flag Attacks
October 10, 2001: Two Israelis Are Detained in Mexican Legislature Building after Behaving Suspiciously and Found To Be Carrying Arms
February 5, 2003: Recently Retired Head of Mossad Says His Agency Has Had Many Secret Big Successes
March 2005: Israel Honors People Involved in Lavon Affair
Early June 2005: US Intelligence Find Evidence of Mossad or CIA Support For Insurgents in Iraq
November 9, 2005: Three Simultaneous Suicide Bombings in Jordan; Israeli Tourists Evacuated in Advance
http://www.historycommons.org/timeline.jsp?western_support_for_islamic_militancy_tmln_alleged_false_flag_operations=western_support_for_islamic_militancy_tmln_israel_and_the_mossad&timeline=western_support_for_islamic_militancy_tmln
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